Exceptional regeneration can be found in some higher animals, such as zebrafish and salamanders. These species are capable of completely regenerating non-lethal injuries and large loss of tissue from internal organs and limbs, producing an organ that is indistinguishable in function from the original, and doing so repeatedly. In mammals, with very few exceptions that occur in only a few species and a few tissues, such injuries only scar with no proficient regeneration. Why is this case? That is the question that many research groups seek to answer, as finding a way to spur regeneration of organs and limbs in our species is obviously a very desirable goal. The authors of today’s paper argue for the use of garfish as an animal model for the investigation
Garfish as a Model for Limb Regeneration
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